EU GMP Standard Hyaluronic Acid Powder For Joint Health / Eyes
Protection
Hyaluronic Acid Powder Function
1. For Joint Health.
People take hyaluronic acid for various joint disorders, including
osteoarthritis. It can be taken by mouth or injected into the
affected joint by a healthcare professional.
2. For Eyes Protection Benefits.
The FDA has approved the use of hyaluronic acid during certain eye
surgeries including cataract removal, corneal transplantation, and
repair of a detached retina and other eye injuries. It is injected
into the eye during the procedure to help replace natural fluids.
3. For Skin Care.
Some people apply hyaluronic acid to the skin for healing wounds,
burns, skin ulcers, and as a moisturizer. It is a critical
component of the skin that helps to retain moisture, keeping the
skin firm, and preventing wrinkles by adding volume to the skin.
Quick features of Hyaluronic Acid Powder
| Material name | Hyaluronic Acid Powder |
| Origin of material | Bacteria Fermentation |
| Color and Apperance | White powder |
| Quality Standard | Injectable grade, with addtional control on the endotoxin |
| Purity of the material | 95%-105% |
| Moisture content | ≤10% (105°for 2hours) |
| Molecular weight | Around 1000 000 Dalton |
| Bulk density | ＞0.35g/ml as bulk density |
| Solubility | Perfect solubility into water |
| Application | Pharma Eye Drop, Burn Topical Ointment |
| GMP Certificate | EU GMP Certificate |
| DMF Documentation | Yes, DMF is available |
| Shelf Life | 2 years from production date |
| Packing | Inner packing: Sealed Foil bag,1KG/Bag, 5KG/Bag |
| Outer packing: 10kg/Fiber drum |
How does Injectable grade HA works for joint health?
1. Sodium hyaluronate is the main component of joint synovial fluid
and is one of the components of the cartilage matrix. It acts as a
lubricant in the joint cavity to reduce the friction between the
tissues, and at the same time exerts an elastic effect, which
cushions the damage of the articular cartilage. Injecting high
molecular weight, high concentration and high elasticity of sodium
hyaluronate into the joint cavity can significantly improve the
inflammatory reaction of synovial tissue, enhance the viscosity and
lubrication function of joint fluid, protect articular cartilage,
and promote the healing and regeneration of articular cartilage.
Relieve pain and increase joint mobility
2. Sodium hyaluronate molecules have a stabilizing effect on joint
pain receptors, and their barrier function can effectively prevent
the diffusion of inflammatory mediators and reduce the stimulation
of chemical receptors on pain receptors. Achieve protection against
joint pain.
3. Hyaluronic acid may also be involved in the synthesis of
cartilage proteoglycan aggregates, so that the normal metabolism of
articular cartilage can be carried out, thereby achieving the
purpose of treating osteoarthritis.
Specification Sheet of Hyaluronic Acid Powder
ITEMS |
SPECIFICATIONS (TEST METHOD) | RESULT |
| Appearance | White or almost white powder or fibrous aggregate | Conforms |
| Identification | | |
| A: Infrared Absorption | Complies with Ph. EUR. Reference spectrum of sodium hyaluronate | Comply |
| B: Reaction of sodium | Postive | Postive |
| Appearance of solution | Clear and the absorbance is NMT 0.01 at 600nm | Clear, A600nm=0.002 |
| Molecular weight | Report the test value | 1.11x 106 Dalton |
| Assay of sodium hyaluronate | 95% -105% | 100% |
| Intrinsic Viscosity | Report the test value | 1.87 m³/kg |
| Loss on drying | Less than10%(USP731) | 8.5% |
| Nucleic Acid | The absorbance is NMT 0.5 at 260nm | 0.06 |
| PH (1%H2O solution) | 5.0-8.5 (0.5% solution) | 6.5 |
| Protein | ≤0.1% (on the dried substance) | 0.03% |
| Chlorides | ≤0.5% | ＜0.5% |
| Heavy Metal | NMT10 PPM | Pass |
| Iron | ≤80 ppm(on the dried substance) | 13.6ppm |
| Residual solvents (Ethanol) | ≤0.5% | 0.008% |
| Microbial Contamination | <100CFU/g | <10CFU/g |
| Bacterial Endotoxins | ＜0.5IU/mg | ＜0.5IU/mg |
